committed to furthering translational studies research in catastrophic diseases to save the lives of humans and pets

 
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The Value of Translational Studies Research

The similarities and resemblances of many diseases that occur in both animals and humans are so numerous that the diseases are virtually identical. With the advent of modern technology like MRIs and the complete mapping of both the human and canine genome, it is apparent that the disease processes are also the same.

In other words, cancer is cancer…not human cancer or dog cancer or ferret cancer…cancer is simply, cancer. Translational research uses this starting point and proceeds to compassionately study naturally occurring diseases in veterinary and human medicine with a goal of sharing data and building from discoveries cooperatively forming a bridge to finding the causes, preventions and cures for catastrophic diseases like; Cancer l Dementia/Alzheimers l Diabetes Crohn's Disease l Arthritis l Hyperthyroidism; Heart Disease l Psychological Disorders (PTSD, anxiety, depression)

Looking at domestic pets in particular offers tremendous insight in translational studies because these animals completely share the human environment and lifestyle. They live in our houses, walk on our fertilized lawns, drive in our cars, eat our leftovers, suffer our stresses…they are models of the human experience that, because of their shorter life spans, run in fast forward.

Translational studies research uses that natural link to explore the real world impact on how disease is generated, grows, and how it can be eradicated…for both humans and pets.

Promising results have emerged through interdisciplinary projects including:

  • Limb-sparing techniques for dogs and teens with bone cancer (developed by physicians and veterinarians at Colorado State University)

  • Treatments for malignant melanoma (developed at Memorial Sloan Kettering and the Animal Medical Center)

  • Organ regeneration and other cancer research (through partnerships between the National Cancer Center's Translational Oncology Program (COP) and veterinary cancer institutions in North America)
    spinal cord injuries (a project between Texas A&M and UCSF).

  • Targeted Molecular Therapies that are in some instances, already being used to treat both dogs and people (at Tufts University) .

  • Epilepsy drugs developed and used in the treatment of epi-dogs are those initially developed for human use.

  •  The first genes responsible for epilepsy syndromes in dogs (discovered jointly by the University of Missouri and the University of Toronto).

  • The senior dog as a spontaneous model for Alzheimer's research that can play a valuable role in developing treatments. Conversely, the knowledge gained from studying Alzheimer's is highly relevant for understanding brain aging and cognitive dysfunction in companion pets.

  • Research on the use of pulsed electromagnetic field therapy in dogs with benign prostatic hyperplasia (BPH), also known as an enlarged prostate, suggests it may hold promise for the nonsurgical treatment in men.



 

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